PXD031572 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomics analysis of physiological effect of ZBTB16 (PLZF) on osteogenic differentiation of human valve interstitial cells (VICs) by DDA PASEF on TimsToF Pro |
Description | During fundamental proteotranscriptomic analysis of human valve interstitial cells (VICs) osteogenic differentiation, we revealed ZBTB16 (PLZF) as one of the most upregulated proteins. Thus, to investigate its physiological role in VICs osteogenic differentiation we performed its overexpression by lentiviral transduction with subsequent proteomics analysis. Despite obvious PLZF overexpression and its reinforcing effect on osteogenic differentiation, we revealed surprisingly small amount of differentially expressed proteins that assumed to be the targets of PLZF. |
HostingRepository | PRIDE |
AnnounceDate | 2022-10-21 |
AnnouncementXML | Submission_2022-10-21_03:30:54.537.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD031572 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | ArseniyLobov |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | acetylated residue; monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue |
Instrument | timsTOF Pro |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-02-10 13:07:15 | ID requested | |
⏵ 1 | 2022-10-21 03:30:54 | announced | |
2 | 2023-11-14 08:54:52 | announced | 2023-11-14: Updated project metadata. |
Publication List
Keyword List
submitter keyword: ZBTB16 |
PLZF |
osteogenic differentiation |
valve interstitial cells |
PASEF |
TimsToF Pro |
Contact List
Anna B.Malashicheva |
contact affiliation | Laboratory of regenerative biomedicine, Institute of Cytology of the Russian Academy of Science |
contact email | amalashicheva@gmail.com |
lab head | |
ArseniyLobov |
contact affiliation | Loboratory of Regenerative Biomedicine, Institute of Cytololgy of the Russian Academy of Science |
contact email | arseniylobov@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/10/PXD031572 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD031572
- Label: PRIDE project
- Name: Proteomics analysis of physiological effect of ZBTB16 (PLZF) on osteogenic differentiation of human valve interstitial cells (VICs) by DDA PASEF on TimsToF Pro