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PXD031174-2

PXD031174 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleAging-Associated Changes in CSF Protein Abundances and Structures Revealed by a Modified LiP-MS Screen
DescriptionWe performed LiP-MS on CSF from young and old mice with a modified analysis pipeline. We found 38 protein groups that change in abundance with aging, most dominantly immunoglobulins of the IgM subclass. We discovered six high-confidence candidates that appeared to change in structure with aging.
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_08:54:12.430.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterSteven Shuken
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListamidated residue; acetylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-01-22 09:54:23ID requested
12022-08-22 13:52:29announced
22023-11-14 08:54:12announced2023-11-14: Updated project metadata.
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Cerebrospinal Fluid, Aging, AD,Mouse, LiP-MS, Human, Limited Proteolysis-Mass Spectrometry, CSF, Alzheimer's Disease
Contact List
Tony Wyss-Coray
contact affiliationDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA
contact emailtwc@stanford.edu
lab head
Steven Shuken
contact affiliationDepartment of Cell Biology, Harvard Medical School
contact emailsrshuken@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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