PXD031027 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | rabbit haemorrhagic disease virus (RHDV) infected rabbit liver proteome |
Description | Rabbit haemorrhagic disease virus (RHDV) belongs to the family Caliciviridae, genus Lagovirus and is used in Australia as a biocontrol tool to keep the population of european rabbits low. This virus has a positive-sense single-stranded RNA genome that encodes structural (capsid) and non-structural proteins. Due to the lack of an established cell culture system for this virus, some of the non-structural proteins are yet awaiting characterisation and their function is unknown. This work attempted to characterise the process of RHDV infection and identify pathways that alterate in RHDV-infected rabbit liver at the proteome level. Young rabbits were infected with RHDV2 (genotype GI.1bP-GI.2) and humanely killed 24 hours post-infection. 25% liver homogenates were prepared in RNAlater buffer and stored at -20C. Uninfected rabbit liver samples served as a control. Samples from three RHDV2-infected animals (K375, K376, K378) and three uninfected animals (K3, K14, K12) were used in this study. |
HostingRepository | PRIDE |
AnnounceDate | 2022-10-14 |
AnnouncementXML | Submission_2022-10-13_20:30:52.732.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | ElenaSmertina |
SpeciesList | scientific name: Oryctolagus cuniculus cuniculus; NCBI TaxID: 568996; |
ModificationList | No PTMs are included in the dataset |
Instrument | LTQ Orbitrap |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-01-17 01:24:57 | ID requested | |
⏵ 1 | 2022-10-13 20:30:53 | announced | |
2 | 2023-11-14 08:01:33 | announced | 2023-11-14: Updated project metadata. |
Publication List
Smertina E, Carroll AJ, Boileau J, Emmott E, Jenckel M, Vohra H, Rolland V, Hands P, Hayashi J, Neave MJ, Liu JW, Hall RN, Strive T, Frese M, Lagovirus Non-structural Protein p23: A Putative Viroporin That Interacts With Heat Shock Proteins and Uses a Disulfide Bond for Dimerization. Front Microbiol, 13():923256(2022) [pubmed] |
Keyword List
submitter keyword: liver, proteome,RHDV, rabbit |
Contact List
TanjaStrive |
contact affiliation | CSIRO Black Mountain, Australia |
contact email | tanja.strive@csiro.au |
lab head | |
ElenaSmertina |
contact affiliation | University of Canberra/CSIRO |
contact email | elena.smertina@csiro.au |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/10/PXD031027 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD031027
- Label: PRIDE project
- Name: rabbit haemorrhagic disease virus (RHDV) infected rabbit liver proteome