PXD029532
PXD029532 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Comparative maternal protein profiling of mouse biparental and uniparental embryos |
| Description | During oogenesis, RNAs and proteins from maternal genome will be accumulated and they are the most important regulatory factors in early embryonic development. Parthenogenesis provides a unique source to investigate the influence of maternal genomes in early mammalian development and is proposed as an experimental tool to investigate embryo development which may solve many of the ethical concerns. Using label-free quantitative mass sepctrometry (MS), we systematically monitored protein expression profiles from six stages during pre-implantation development used by parthenogenesis model of mouse: pronucleus-, 2-cell, 4-cell, and 8-cell embryo, morula, and blastocyst. They are labeled as PA, PA-2, PA-4, PA-8, PAMO, PABL, respectively. For each stage, 6,000 embryos were used, and the experiment was performed in three biological replicates, and they had 2,048 proteins in common. |
| HostingRepository | iProX |
| AnnounceDate | 2022-07-15 |
| AnnouncementXML | Submission_2022-10-13_19:33:38.433.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Fumei Chen |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive; Orbitrap Fusion |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2021-11-02 22:32:28 | ID requested | |
| 1 | 2022-02-27 21:11:25 | announced | |
| 2 | 2022-07-17 20:07:07 | announced | 2022-07-18: Update information. |
| ⏵ 3 | 2022-10-13 19:33:39 | announced | 2022-07-18: Update information. 2022-10-14: Update publication information. |
Publication List
| Chen F, Ma B, Lin Y, Luo X, Xu T, Zhang Y, Chen F, Li Y, Zhang Y, Luo B, Zhang Q, Xie X, Comparative maternal protein profiling of mouse biparental and uniparental embryos. Gigascience, 11():(2022) [pubmed] |
Keyword List
| submitter keyword: maternal genome, proteomic, parthenogenesis, pre-implantation development, embryo |
Contact List
| Fumei Chen | |
|---|---|
| contact affiliation | Guangxi Medical University |
| contact email | gxchenfumei@163.com |
| lab head | |
| Fumei Chen | |
| contact affiliation | Guangxi Medical University |
| contact email | gxchenfumei@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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