PXD028979 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomic and phosphoproteomic profilings in fibroblasts of 11 common mammalian species |
Description | A central goal of modern biology is to understand the molecular basis of phenotype evolution between species. Previously, the evolutionary profiling at the molecular level has been largely limited to the nucleotide level. Nevertheless, the genotype is translated to proteotype through comprehensive and gene-specific post-transcriptional regulations. Harnessing recently emerged consistent proteomic quantification methods, we here investigate the co-evolution processes across the transcriptomic, proteomic, and phosphoproteomic layers in skin fibroblasts from 11 common mammalian species. Altogether, we have generated a multi-species, multi-omics resource, the analysis of which significantly facilitates the understanding of gene expression, proteotype co-evolution, and biodiversity in mammals. |
HostingRepository | PRIDE |
AnnounceDate | 2022-09-22 |
AnnouncementXML | Submission_2022-09-21_21:51:06.863.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Wenxue Li |
SpeciesList | scientific name: Equus caballus; NCBI TaxID: 9796; scientific name: Macaca mulatta; NCBI TaxID: 9544; scientific name: Oryctolagus cuniculus; NCBI TaxID: 9986; scientific name: Bos taurus (Bovine); NCBI TaxID: 9913; scientific name: Ovis aries; NCBI TaxID: 9940; scientific name: Monodelphis domestica; NCBI TaxID: 13616; scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116; scientific name: Homo sapiens (Human); NCBI TaxID: 9606; scientific name: Canis lupus; NCBI TaxID: 9612; scientific name: Felis catus; NCBI TaxID: 9685; scientific name: Sus scrofa; NCBI TaxID: 9823; |
ModificationList | phosphorylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-10-07 00:28:37 | ID requested | |
⏵ 1 | 2022-09-21 21:51:07 | announced | |
2 | 2023-11-14 08:53:54 | announced | 2023-11-14: Updated project metadata. |
Publication List
Keyword List
submitter keyword: Phosphoproteomics, quantitative proteomics, multiple species, DIA-MS |
Contact List
Yansheng Liu |
contact affiliation | Department of Pharmacology, Yale University School of Medicine |
contact email | yansheng.liu@yale.edu |
lab head | |
Wenxue Li |
contact affiliation | Yale University |
contact email | wenxue.li@yale.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD028979
- Label: PRIDE project
- Name: Proteomic and phosphoproteomic profilings in fibroblasts of 11 common mammalian species