PXD028950

PXD028950 is an original dataset announced via ProteomeXchange.

Title	Impact of fetal growth restriction on neonatal microglia proteome in rat.
Description	Microglia activation is a key modulator of brain vulnerability in response to intra-uterine growth restriction (IUGR). However, the consequences of IUGR on microglia development and on microglia proteome are still unknown. We used a model of IUGR induced by a gestational low-protein diet (LPD) in rat. Microglia were isolated from control and LPD animals at P1 and P4. The aim of this work was characterize the consequence of IUGR on microglia development and investigate the consequences of IUGR exposure on microglia proteome during the first postnatal days using a bioinformatics approach associated with functional assays.
HostingRepository	PRIDE
AnnounceDate	2021-12-17
AnnouncementXML	Submission_2021-12-17_07:13:40.575.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Virginie Salnot
SpeciesList	scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2021-10-05 05:41:43	ID requested
⏵ 1	2021-12-17 07:13:41	announced

Zinni M, Pansiot J, Colella M, Faivre V, Delahaye-Duriez A, Guillonneau F, Bruce J, Salnot V, Mairesse J, Knoop M, Possovre ML, Vaiman D, Baud O, Impact of Fetal Growth Restriction on the Neonatal Microglial Proteome in the Rat. Nutrients, 13(11):(2021) [pubmed]

submitter keyword: microglia

IUGR

inflammation

proteome

brain development

mass spectrometry

Olivier Baud
contact affiliation	Université de Paris, Inserm UMR 1141 NeuroDiderot, F-75019Paris
contact email	olivier.baud@hcuge.ch
lab head
Virginie Salnot
contact affiliation	3p5-proteom'ic plateform
contact email	virginie.salnot@parisdescartes.fr
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/12/PXD028950

PRIDE project URI

• PRIDE
  1. PXD028950
     1. Label: PRIDE project
     2. Name: Impact of fetal growth restriction on neonatal microglia proteome in rat.