PXD028766-1
PXD028766 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | The proteomics of RNA-binding protein RbpA and the macrophages-treatment Streptococcus suis |
Description | Streptococcus suis serotype 2 (SS2) is an important zoonotic pathogen responsible for various swine diseases and human cases of streptococcal toxic shock syndrome. RNA-binding protein RbpA can modulate gene expression through post-transcriptional regulation. Macrophages are one of the host immune cells and play an important role in resisting the invasion of pathogens such as bacteria. The potential targets of RbpA were analyzed by comparing the proteome of rbpA gene deletion strain (△rbpA) and parent strain (ZY05719). In addition, raw macrophages were used to incubate the parent bacteria to obtain the treatment group (macrophages treated ZY05719, recorded as macrophages group). The proteomic differences between the treatment group and ZY05719 group were compared to analyze the potential mechanism of Streptococcus suis against macrophage killing. |
HostingRepository | iProX |
AnnounceDate | 2021-09-27 |
AnnouncementXML | Submission_2021-09-26_20:59:37.584.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Xiaojun Zhong |
SpeciesList | scientific name: Streptococcus suis 05ZYH33; NCBI TaxID: 391295; |
ModificationList | TMT6plex reporter fragment |
Instrument | LTQ |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2021-09-26 20:57:57 | ID requested | |
⏵ 1 | 2021-09-26 20:59:37 | announced |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Streptococcus suis, RNA-binding protein, RbpA, Macrophages |
Contact List
Huochun Yao | |
---|---|
contact affiliation | Nanjing Agricultural University |
contact email | yaohch@njau.edu.cn |
lab head | |
Xiaojun Zhong | |
contact affiliation | Zhejiang A & F University |
contact email | xjzhong@zafu.edu.cn |
dataset submitter |
Full Dataset Link List
iProX dataset URI |