PXD027651-2
PXD027651 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Novel roles of small extracellular vesicles in regulating the quiescence and proliferation of neural stem cells |
Description | We analyzed protein cargos of NSC sEVs from proliferating, resting and reactivating status by proteomics approaches. Our results revealed specific functional clusters of pathways in gene ontology annotations of differentially expressed proteins in three sources of exosomes. Furthermore, we showed the involvement of sEVs in maintaining quiescence, along with entering and exiting the G0 phase by applying an exosome inhibitor. Our findings highlighted the expression level changes of NSCs of sEV protein cargo at different proliferative conditions and further confirmed the involvement of sEVs in entering, maintaining and exiting quiescence of NSCs. |
HostingRepository | jPOST |
AnnounceDate | 2021-10-27 |
AnnouncementXML | Submission_2022-09-18_02:17:35.285.xml |
DigitalObjectIdentifier | |
ReviewLevel | Non peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Koshi Imami |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | S-carboxamidomethyl-L-cysteine; alpha-amino acetylated residue; L-methionine sulfoxide |
Instrument | LTQ Orbitrap |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2021-07-29 23:55:31 | ID requested | |
1 | 2021-10-27 01:34:43 | announced | |
⏵ 2 | 2022-09-18 02:17:35 | announced | 2022-09-18: Updated FTP location. |
3 | 2024-03-12 19:36:17 | announced | 2024-03-13: Updated PubMed. |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: extracellular vesicles, neural stem cells |
Contact List
Taeko Kobayashi | |
---|---|
lab head | |
Koshi Imami | |
contact affiliation | Kyoto University |
dataset submitter |
Full Dataset Link List
jPOST dataset URI |
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST001276/ |