PXD027593 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Amorphous silica nanoparticle exposures can lead to mitochondrial protein changes |
Description | Mitochondrial fractions from J774 mouse macrophage/monocyte cells were exposed to amorphous silica nanoforms and mitochondrial protein profiles were examined to gain information on relative toxicities of these nanomaterials on mitochondrial pathways and identify potency determinants, for risk characterization. The applicability of this approach for screening mitochondrial toxicity of nanomaterials was also verified. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_08:53:07.632.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Sadhna Phanse |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | No PTMs are included in the dataset |
Instrument | LTQ Orbitrap Elite |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-07-27 07:27:21 | ID requested | |
1 | 2023-03-22 09:13:40 | announced | |
⏵ 2 | 2023-11-14 08:53:08 | announced | 2023-11-14: Updated project metadata. |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: proteomics, mass spectrometry, exposure, physicochemical characteristics, mitochondria,Amorphous silica nanomaterials, nanoforms |
Contact List
Dr. Prem Kumarathasan |
contact affiliation | 1. Environmental Health Science and Research Bureau, HECSB, Health Canada, Ottawa, ON 2. Interdisciplinary School of Health Sciences, Faculty of Health Sciences, University of Ottawa, Ottawa, ON |
contact email | premkumari.kumarathasan@canada.ca |
lab head | |
Sadhna Phanse |
contact affiliation | University of Toronto; University of Regina |
contact email | srphanse@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD027593
- Label: PRIDE project
- Name: Amorphous silica nanoparticle exposures can lead to mitochondrial protein changes