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PXD027593

PXD027593 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleAmorphous silica nanoparticle exposures can lead to mitochondrial protein changes
DescriptionMitochondrial fractions from J774 mouse macrophage/monocyte cells were exposed to amorphous silica nanoforms and mitochondrial protein profiles were examined to gain information on relative toxicities of these nanomaterials on mitochondrial pathways and identify potency determinants, for risk characterization. The applicability of this approach for screening mitochondrial toxicity of nanomaterials was also verified.
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_08:53:07.632.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterSadhna Phanse
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumentLTQ Orbitrap Elite
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-07-27 07:27:21ID requested
12023-03-22 09:13:40announced
22023-11-14 08:53:08announced2023-11-14: Updated project metadata.
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: proteomics, mass spectrometry, exposure, physicochemical characteristics, mitochondria,Amorphous silica nanomaterials, nanoforms
Contact List
Dr. Prem Kumarathasan
contact affiliation1. Environmental Health Science and Research Bureau, HECSB, Health Canada, Ottawa, ON 2. Interdisciplinary School of Health Sciences, Faculty of Health Sciences, University of Ottawa, Ottawa, ON
contact emailpremkumari.kumarathasan@canada.ca
lab head
Sadhna Phanse
contact affiliationUniversity of Toronto; University of Regina
contact emailsrphanse@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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