PXD027513-2
PXD027513 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | PUMILIO Proteins in Colorectal Cancer: Tumor Growth Promoting Function and Potential as Therapeutic Targets |
Description | We employ Mass spectrum to investigate proteome of Pum1-Knockout, Pum2-Knockout and WT conditions in human colorectal cancer cell line Hct116. Overall design: In order to investigate whether Pum1 and Pum2 regulate their targets at their protein levels, we used Pum1-Knockout, Pum2-Knockout and WT Hct116 cell line to extract total protein for Mass spectrum. |
HostingRepository | iProX |
AnnounceDate | 2021-07-23 |
AnnouncementXML | Submission_2023-02-02_19:04:59.175.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Yuanyuan Gong |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | TMT6plex reporter+balance reagent acylated residue; iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2021-07-22 23:21:32 | ID requested | |
1 | 2023-01-03 02:03:50 | announced | |
⏵ 2 | 2023-02-02 19:05:00 | announced | 2023-02-03: Update publication information. |
Publication List
Gong Y, Liu Z, Yuan Y, Yang Z, Zhang J, Lu Q, Wang W, Fang C, Lin H, Liu S, PUMILIO proteins promote colorectal cancer growth via suppressing p21. Nat Commun, 13(1):1627(2022) [pubmed] |
Keyword List
submitter keyword: human colorectal cancer, Pumilio protein, TMT, LC-MS |
Contact List
Haifan Lin | |
---|---|
contact affiliation | Shanghai Institute for Advanced Immunochemical Studies |
contact email | linhf@shanghaitech.edu.cn |
lab head | |
Yuanyuan Gong | |
contact affiliation | Shanghai Institute for Advanced Immunochemical Studies |
contact email | 944942666@qq.com |
dataset submitter |
Full Dataset Link List
iProX dataset URI |