PXD027405 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | iTRAQ-based Quantitative Proteomics Analysis of protein profile response to Pink1 deletion in breast cancer |
Description | ITRAQ technique was applied to compare the comprehensive protein expression profiles between MDA-MB-231con and MDA-MB-231Pink1-/- cells, and the original mass spectrum data were searched using Mascot engine against the UniProt database and the decoy database. Proteins were identified to be significantly according to the cut-off of a fold change ≥1.2 or ≤0.83 and a P-value <0.05. All of the pathways and GO enrichment analyses were performed to identify the critical proteins induced by Pink1 deletion. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_08:38:40.343.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Liqin Li |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | iTRAQ8plex-116 reporter+balance reagent acylated residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-07-19 02:37:14 | ID requested | |
1 | 2023-03-10 23:44:50 | announced | |
⏵ 2 | 2023-11-14 08:38:42 | announced | 2023-11-14: Updated project metadata. |
Publication List
Li J, Xu X, Huang H, Li L, Chen J, Ding Y, Ping J, promotes cell proliferation and affects glycolysis in breast cancer. Exp Biol Med (Maywood), 247(12):985-995(2022) [pubmed] |
Keyword List
submitter keyword: Human,Pink1,metabolism,Breast Cancer |
Contact List
LiQin Li |
contact affiliation | Huzhou Key labratory of Molecular Medicine, Huzhou Central Hospital,Huzhou,China. |
contact email | liliqin@hzhospital.com |
lab head | |
Liqin Li |
contact affiliation | Huzhou Cent Hosp, Affiliated Cent Hosp HuZhou University |
contact email | liliqin@hzhospital.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/03/PXD027405 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD027405
- Label: PRIDE project
- Name: iTRAQ-based Quantitative Proteomics Analysis of protein profile response to Pink1 deletion in breast cancer