PXD027405

PXD027405 is an original dataset announced via ProteomeXchange.

Title	iTRAQ-based Quantitative Proteomics Analysis of protein profile response to Pink1 deletion in breast cancer
Description	ITRAQ technique was applied to compare the comprehensive protein expression profiles between MDA-MB-231con and MDA-MB-231Pink1-/- cells, and the original mass spectrum data were searched using Mascot engine against the UniProt database and the decoy database. Proteins were identified to be significantly according to the cut-off of a fold change ≥1.2 or ≤0.83 and a P-value ＜0.05. All of the pathways and GO enrichment analyses were performed to identify the critical proteins induced by Pink1 deletion.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:38:40.343.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Liqin Li
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iTRAQ8plex-116 reporter+balance reagent acylated residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2021-07-19 02:37:14	ID requested
1	2023-03-10 23:44:50	announced
⏵ 2	2023-11-14 08:38:42	announced	2023-11-14: Updated project metadata.

Li J, Xu X, Huang H, Li L, Chen J, Ding Y, Ping J, promotes cell proliferation and affects glycolysis in breast cancer. Exp Biol Med (Maywood), 247(12):985-995(2022) [pubmed]

submitter keyword: Human,Pink1,metabolism,Breast Cancer

LiQin Li
contact affiliation	Huzhou Key labratory of Molecular Medicine, Huzhou Central Hospital,Huzhou,China.
contact email	liliqin@hzhospital.com
lab head
Liqin Li
contact affiliation	Huzhou Cent Hosp, Affiliated Cent Hosp HuZhou University
contact email	liliqin@hzhospital.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/03/PXD027405

PRIDE project URI

• PRIDE
  1. PXD027405
     1. Label: PRIDE project
     2. Name: iTRAQ-based Quantitative Proteomics Analysis of protein profile response to Pink1 deletion in breast cancer