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PXD027311-1

PXD027311 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleDrone honey bees are disproportionately sensitive to abiotic stressors relative to workers, despite expressing high levels of stress response proteins
DescriptionDrone honey bees are the obligate sexual partners of queens, and the availability of healthy, high-quality drones directly affects the queen's fertility and the productivity of her subsequent colony. Yet, our understanding of how stressors affect drone fertility and physiology is presently limited. Like other male Hymenopterans, drones are haploid and are thus expected to be more sensitive to stressors than workers, as suggested by the haploid susceptibility hypothesis. We used quantitative proteomics to investigate protein expression profiles in the hemolymph of topically exposed workers and drones, and we show that drones express surprisingly high levels of putative stress response proteins - even in the negative control groups - relative to workers. These findings suggest that drones may invest in strong constitutive expression of damage-mitigating proteins for a wide range of stressors, potentially to the detriment of launching a more specific response to new stressors. Regardless of the underlying mechanism, the robust expression patterns of proteins involved in stress responses in drones suggests that drone stress tolerance systems are fundamentally rewired relative to workers, and their susceptibility to stress depends on more than simply gene dose or deleterious recessive alleles.
HostingRepositoryMassIVE
AnnounceDate2021-12-21
AnnouncementXMLSubmission_2021-12-21_23:26:31.597.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAlison McAfee
SpeciesList scientific name: Apis mellifera; common name: honey bee; NCBI TaxID: 7460;
ModificationListunknown modification; unknown modification; unknown modification
Instrumentinstrument model; instrument model
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-07-14 10:22:56ID requested
12021-12-21 23:26:31announced
Publication List
no publication
Keyword List
submitter keyword: Honey bees, Stress response, Pesticides, Detoxification, Drones , Workers
Contact List
Leonard Foster
contact affiliationUniversity of British Columbia
contact emailfoster@msl.ubc.ca
lab head
Alison McAfee
contact affiliationUniversity of British Columbia
contact emailalison.mcafee@alumni.ubc.ca
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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