PXD026994 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | In-depth proteome analysis of brain tissue from Ewsr1 gene knock-out mice |
Description | Ewing’s Sacroma (EWS) is a carcinogenic bone tumor which is predominantly occurred in young adults. EWS RNA binding protein 1 (Ewsr1) protein is well-known as a multifunctional protein and its epigenetic signatures contribute to the pathogenesis of various human disease such as neurodegenerative disorders, skin development, or tumorigenic process. However, the specific cellular function and physiological characteristics of Ewsr1 are still ambiguous. In this study, therefore, we applied TMT-labeled quantitative mass spectrometry-based proteomic approach to investigate the global proteome changes of brain tissue between Ewsr1 knock-out (KO) and wild type (WT) mice (n=3, each). |
HostingRepository | PRIDE |
AnnounceDate | 2023-01-16 |
AnnouncementXML | Submission_2023-01-16_01:54:08.596.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | DohyunHan |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive Plus |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-06-29 08:06:54 | ID requested | |
⏵ 1 | 2023-01-16 01:54:08 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Ewsr1, mice, tandem mass tag |
Contact List
DohyunHan |
contact affiliation | Proteomics core facility, Biomedical Research Institute, Seoul National University Hospital |
contact email | hdh03@snu.ac.kr |
lab head | |
DohyunHan |
contact affiliation | Proteomics Core Facility, Biomedical Research Institute, Seoul National University Hospital |
contact email | hdh03@snu.ac.kr |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD026994
- Label: PRIDE project
- Name: In-depth proteome analysis of brain tissue from Ewsr1 gene knock-out mice