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PXD026994

PXD026994 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleIn-depth proteome analysis of brain tissue from Ewsr1 gene knock-out mice
DescriptionEwing’s Sacroma (EWS) is a carcinogenic bone tumor which is predominantly occurred in young adults. EWS RNA binding protein 1 (Ewsr1) protein is well-known as a multifunctional protein and its epigenetic signatures contribute to the pathogenesis of various human disease such as neurodegenerative disorders, skin development, or tumorigenic process. However, the specific cellular function and physiological characteristics of Ewsr1 are still ambiguous. In this study, therefore, we applied TMT-labeled quantitative mass spectrometry-based proteomic approach to investigate the global proteome changes of brain tissue between Ewsr1 knock-out (KO) and wild type (WT) mice (n=3, each).
HostingRepositoryPRIDE
AnnounceDate2023-01-16
AnnouncementXMLSubmission_2023-01-16_01:54:08.596.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterDohyunHan
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive Plus
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-06-29 08:06:54ID requested
12023-01-16 01:54:08announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Ewsr1, mice, tandem mass tag
Contact List
DohyunHan
contact affiliationProteomics core facility, Biomedical Research Institute, Seoul National University Hospital
contact emailhdh03@snu.ac.kr
lab head
DohyunHan
contact affiliationProteomics Core Facility, Biomedical Research Institute, Seoul National University Hospital
contact emailhdh03@snu.ac.kr
dataset submitter
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Dataset FTP location
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