PXD026758-1
PXD026758 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | RasimBarutcu_MingkunWu_et_al_APEX_2021 |
Description | This dataset consists of 26 raw MS files and associated peak lists and result files, acquired on a TripleTOF 6600 mass spectrometer operated in Data Dependent Acquisition mode. Samples were generated by Rasim Barutcu and Mingkun Wu (some clones also generated by Boris Dyakov). Streptavidin affinity purification and mass spectrometric acquisition was performed by Zhen-Yuan Lin. Mass Spectrometry data analysis was performed by Boris Dyakov. The files are associated with a manuscript submitted for publication by Barutcu et al. that identifies functionally distinct proteins and retained intron RNAs associated with nuclear domains (speckles and lamina) using APEX2-mediated proximity labeling. ("Systematic mapping of nuclear domain associated transcripts reveals speckles and lamina as hubs of functionally distinct populations of retained introns") Benjamin Blencowe is the corresponding author of the manuscript (b.blencowe@utoronto.ca). Anne-Claude Gingras should be contacted for questions about this dataset (gingras@lunenfeld.ca). |
HostingRepository | MassIVE |
AnnounceDate | 2023-01-10 |
AnnouncementXML | Submission_2023-01-10_10:41:38.027.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Gingras Lab |
SpeciesList | scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606; |
ModificationList | deamidated L-asparagine; deamidated L-glutamine; L-methionine sulfoxide |
Instrument | TripleTOF 6600 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2021-06-17 13:06:36 | ID requested | |
⏵ 1 | 2023-01-10 10:41:38 | announced |
Publication List
Barutcu AR, Wu M, Braunschweig U, Dyakov BJA, Luo Z, Turner KM, Durbic T, Lin ZY, Weatheritt RJ, Maass PG, Gingras AC, Blencowe BJ, Systematic mapping of nuclear domain-associated transcripts reveals speckles and lamina as hubs of functionally distinct retained introns. Mol Cell, 82(5):1035-1052.e9(2022) [pubmed] |
Keyword List
submitter keyword: Proximity-dependent biotinylation, APEX, RNA, Nuclear bodies, Speckles, Lamina, Nuclear domains, Retained introns |
Contact List
Anne-Claude Gingras | |
---|---|
contact affiliation | LTRI |
contact email | gingras@lunenfeld.ca |
lab head | |
Gingras Lab | |
contact affiliation | Samuel Lunenfeld Research Institute |
contact email | gingras@mshri.on.ca |
dataset submitter |
Full Dataset Link List
MassIVE dataset URI |
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