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PXD025662-2

PXD025662 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMolecular architecture of the human tRNA ligase complex
DescriptionChemical cross-linking coupled to mass spectrometry was used to study two tRNA ligase complexes, one consisting of subunits RTCB, DDX1, CGI-99, FAM98B and Ashwin (“full tRLC”) and one lacking Ashwin (“core tRLC”). Cross-linking was performed using the homobifunctional, noncleavable reagent, disuccinimidyl suberate (DSS).
HostingRepositoryPRIDE
AnnounceDate2021-12-15
AnnouncementXMLSubmission_2021-12-20_11:33:31.822.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAlexander Leitner
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListiodoacetamide derivatized residue
InstrumentLTQ Orbitrap Elite
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-04-27 08:33:46ID requested
12021-12-15 02:28:57announced
22021-12-20 11:33:32announced2021-12-20: Updated publication reference for PubMed record(s): 34854379.
Publication List
Kroupova A, Ackle F, Asanovi, ć I, Weitzer S, Boneberg FM, Faini M, Leitner A, Chui A, Aebersold R, Martinez J, Jinek M, Molecular architecture of the human tRNA ligase complex. Elife, 10():(2021) [pubmed]
Keyword List
submitter keyword: Chemical cross-linking
DSS
structural proteomics
protein complex
tRNA ligase complex
Contact List
Martin Jinek
contact affiliationDepartment of Biochemistry, University of Zurich, Zurich, Switzerland
contact emailjinek@bioc.uzh.ch
lab head
Alexander Leitner
contact affiliationETH Zurich, Institute of Molecular Systems Biology
contact emailleitner@imsb.biol.ethz.ch
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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