PXD025613
PXD025613 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Application of an iPSC-derived Organoid Model for Located Scleroderma Therapy |
Description | Scleroderma is a chronic connective tissue disease characterized by skin thickening and plaque morphea, as well as hard, shiny skin. Serious involvement is observed from the superficial dermis down to the fascia and muscle. However, this condition is difficult to treat and evaluate. In this study, induced pluripotent stem cell (iPSC)-derived 3D epithelial and mesenchymal organoids were used for localized scleroderma therapy. |
HostingRepository | iProX |
AnnounceDate | 2021-04-26 |
AnnouncementXML | Submission_2022-11-22_01:03:12.158.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Jie Ma |
SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
ModificationList | acetylated residue; iodoacetamide derivatized residue; monohydroxylated residue |
Instrument | Orbitrap Fusion |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2021-04-25 21:55:25 | ID requested | |
⏵ 1 | 2022-11-22 01:03:12 | announced |
Publication List
Ma J, Li W, Cao R, Gao D, Zhang Q, Li X, Li B, Lv L, Li M, Jiang J, Wang Y, Li J, Wu Z, Zhu Y, Zhong W, Zhang S, Leng L, Application of an iPSC-Derived Organoid Model for Localized Scleroderma Therapy. Adv Sci (Weinh), 9(16):e2106075(2022) [pubmed] |
Keyword List
submitter keyword: Scleroderma, organoid, proteomics, therapy |
Contact List
Ling Leng | |
---|---|
contact affiliation | Department of Medical Science Research Center, Peking Union Medical College Hospital. |
contact email | zhenlinger@126.com |
lab head | |
Jie Ma | |
contact affiliation | National Center for Protein Sciences (Beijing), Beijing Institute of Life Omics. |
contact email | majie729@163.com |
dataset submitter |
Full Dataset Link List
iProX dataset URI |