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PXD025068 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleShell protein degradation by TMT- LC-MS/MS
DescriptionThis study investigates the degradation of mineral-associated proteins from Spondylus gaederopus mollusc shell. We analysed intracrystalline proteins extracted from powdered shell samples that were artificially aged by heating at 110 °C for different time durations (0, 1, 2, 4, 8, 16, 24, 48, 96, 240 h). TMT-labelled quantitative proteomics was used to study the degradation pathways and to identify peptide bonds that were unstable and prone to hydrolysis.
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterJorune Sakalauskaite
SpeciesList scientific name: Spondylus gaederopus; NCBI TaxID: 235612;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue; deamidated residue
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-03-29 06:48:42ID requested
12021-11-25 04:45:20announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Shells, quantitative proteomics, protein degradation, intracrystalline proteins
Contact List
Beatrice Demarchi
contact affiliationDepartment of Life Sciences and Systems Biology, University of Turin, Italy
contact emailbeatrice.demarchi@unito.it
lab head
Jorune Sakalauskaite
contact affiliationUniversity of Turin
contact emailjorune.sakalauskaite@unito.it
dataset submitter
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