PXD024560-1
PXD024560 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Discovery of a cooperative mode of inhibiting RIPK1 kinase |
Description | By using Limited Proteolysis-Mass Spectrometry (LiP-MS) and Hydrogen Deuterium Exchange-Mass Spectrometry (HDX-MS) analysis, we identified the binding pocket of Nec-34 in RIPK1 kinase domain. This newly identified binding pocket of Nec-34 is distinct from distinct from that of Nec-1s. |
HostingRepository | iProX |
AnnounceDate | 2021-03-07 |
AnnouncementXML | Submission_2021-03-07_03:38:42.079.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Ying Li |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive; LTQ Orbitrap Elite |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2021-03-07 03:35:08 | ID requested | |
⏵ 1 | 2021-03-07 03:38:42 | announced | |
2 | 2023-08-28 00:28:24 | announced | 2023-08-28: Update information. |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: RIPK1 inhibitor |
Contact List
Ying Li | |
---|---|
contact affiliation | Interdisciplinary Research Center on Biology and Chemistry |
contact email | liying@sioc.ac.cn |
lab head | |
Ying Li | |
contact affiliation | Interdisciplinary Research Center on Biology and Chemistry |
contact email | liying@sioc.ac.cn |
dataset submitter |
Full Dataset Link List
iProX dataset URI |