PXD024560

PXD024560 is an original dataset announced via ProteomeXchange.

Title	Discovery of a cooperative mode of inhibiting RIPK1 kinase
Description	By using Limited Proteolysis-Mass Spectrometry (LiP-MS) and Hydrogen Deuterium Exchange-Mass Spectrometry (HDX-MS) analysis, we identified the binding pocket of Nec-34 in RIPK1 kinase domain. This newly identified binding pocket of Nec-34 is distinct from distinct from that of Nec-1s.
HostingRepository	iProX
AnnounceDate	2021-03-07
AnnouncementXML	Submission_2023-08-28_00:28:23.635.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ying Li
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive; LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2021-03-07 03:35:08	ID requested
1	2021-03-07 03:38:42	announced
⏵ 2	2023-08-28 00:28:24	announced	2023-08-28: Update information.

Meng H, Wu G, Zhao X, Wang A, Li D, Tong Y, Jin T, Cao Y, Shan B, Hu S, Li Y, Pan L, Tian X, Wu P, Peng C, Yuan J, Li G, Tan L, Wang Z, Li Y, Discovery of a cooperative mode of inhibiting RIPK1 kinase. Cell Discov, 7(1):41(2021) [pubmed]

submitter keyword: RIPK1 inhibitor

Ying Li
contact affiliation	Interdisciplinary Research Center on Biology and Chemistry
contact email	liying@sioc.ac.cn
lab head
Ying Li
contact affiliation	Interdisciplinary Research Center on Biology and Chemistry
contact email	liying@sioc.ac.cn
dataset submitter

iProX dataset URI