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PXD024243-1

PXD024243 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleCellular proteomic changes in the immediate early phase of HIV-1 and 2 transduction
DescriptionHuman immunodeficiency viruses type 1 and 2 (HIV-1 and 2) are known to depend on cellular host machinery for their replication and survival. While most of the studies on cellular proteomic and transcriptomic changes focused on the late-phase of the infection, studies of those changes in the early time-points; especially in the case of HIV-2 infection, are widely lacking. Using 2nd generation HIV-1 and 2 VSV-G pseudotyped lentiviral vectors, we transduced HEK-293T cells, and carried out transcriptomic profiling and proteomic analysis of harvested cells at 2h time point, which is representative of the immediate early-phase events in the infection cycle.
HostingRepositoryPRIDE
AnnounceDate2021-11-03
AnnouncementXMLSubmission_2021-11-03_07:53:11.505.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD024243
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterGergő Kalló
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
InstrumentLTQ Orbitrap
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-02-18 10:11:48ID requested
12021-11-03 07:53:11announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: HIV-1, HIV-2, cellular proteome change
Contact List
Jozsef Tozser
contact affiliationDepartment of Biochemistry and Molecular Biology, University of Debrecen, Hungary
contact emailtozser@med.unideb.hu
lab head
Gergő Kalló
contact affiliationUniversity of Debrecen
contact emailkallo.gergo@med.unideb.hu
dataset submitter
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Dataset FTP location
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PRIDE project URI
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