PXD023440

PXD023440 is an original dataset announced via ProteomeXchange.

Title	Prevention of high fat diet induced obesity and associated disease by the major cap-binding protein
Description	Employing genome-wide mass spectrometry and metabolomics, our findings reveal that eIF4E selectively facilitates translation of genes involved in lipid storage and lipid homeostasis pathways in response to fatty acid stimuli.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_09:05:46.242.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Juan Oses-Prieto
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2021-01-06 03:56:26	ID requested
1	2023-10-05 10:25:43	announced
⏵ 2	2023-11-14 09:05:47	announced	2023-11-14: Updated project metadata.

Conn CS, Yang H, Tom HJ, Ikeda K, Oses-Prieto JA, Vu H, Oguri Y, Nair S, Gill RM, Kajimura S, DeBerardinis RJ, Burlingame AL, Ruggero D, The major cap-binding protein eIF4E regulates lipid homeostasis and diet-induced obesity. Nat Metab, 3(2):244-257(2021) [pubmed]

submitter keyword: Obesity, translational control, lipid homeostasis, eFT508, eIF4E

Davide Ruggero
contact affiliation	Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA School of Medicine and Department of Urology, UCSF, CA, USA Department of Cellular and Molecular Pharmacology, UCSF, CA, USA
contact email	Davide.Ruggero@ucsf.edu
lab head
Juan Oses-Prieto
contact affiliation	UCSF
contact email	joses@cgl.ucsf.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/10/PXD023440

PRIDE project URI

• PRIDE
  1. PXD023440
     1. Label: PRIDE project
     2. Name: Prevention of high fat diet induced obesity and associated disease by the major cap-binding protein