PXD022817-1

PXD022817 is an original dataset announced via ProteomeXchange.

Title	COVIDomics_plasma_2020_DDA-PASEF
Description	In order to investigate variations in the endotype of COVID19 patients, we completed an integrated analysis of 112 research participants, including 74 COVID19 patients versus 37 SARS-CoV-2 negative controls. COVID19 patients tested positive for SARS-CoV-2 infection by PCR and/or antibody testing and were hospitalized due to COVID19 symptoms, but none of them had developed severe pathology requiring ICU admission at the time of blood collection. The control group was recruited from the same hospital system but tested negative for SARS-CoV-2 infection. Research blood draws were obtained from consented participants and analyzed by matched SARS-CoV-2 seroconversion assays, plasma proteomics using two alternative platforms [mass-spectrometry (MS), and SOMAscan assays], 82-plex cytokine profiling using Meso Scale Discovery (MSD) assays, and immune cell profiling via mass cytometry (MC).
HostingRepository	PRIDE
AnnounceDate	2021-03-04
AnnouncementXML	Submission_2021-03-03_22:55:59.602.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Kirk Hansen
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Bruker Daltonics BioTOF series

Revision	Datetime	Status	ChangeLog Entry
0	2020-11-30 03:59:04	ID requested
⏵ 1	2021-03-03 22:55:59	announced

Dataset with its publication pending

ProteomeXchange project tag: Covid-19

submitter keyword: plasma, COVID-19, multi-omics

Kirk Hansen
contact affiliation	Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, USA
contact email	kirk.hansen@cuanschutz.edu
lab head
Kirk Hansen
contact affiliation	University of Colorado
contact email	kirk.hansen@ucdenver.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/03/PXD022817

PRIDE project URI

• PRIDE
  1. PXD022817
     1. Label: PRIDE project
     2. Name: COVIDomics_plasma_2020_DDA-PASEF