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PXD022817

PXD022817 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleCOVIDomics_plasma_2020_DDA-PASEF
DescriptionIn order to investigate variations in the endotype of COVID19 patients, we completed an integrated analysis of 112 research participants, including 74 COVID19 patients versus 37 SARS-CoV-2 negative controls. COVID19 patients tested positive for SARS-CoV-2 infection by PCR and/or antibody testing and were hospitalized due to COVID19 symptoms, but none of them had developed severe pathology requiring ICU admission at the time of blood collection. The control group was recruited from the same hospital system but tested negative for SARS-CoV-2 infection. Research blood draws were obtained from consented participants and analyzed by matched SARS-CoV-2 seroconversion assays, plasma proteomics using two alternative platforms [mass-spectrometry (MS), and SOMAscan assays], 82-plex cytokine profiling using Meso Scale Discovery (MSD) assays, and immune cell profiling via mass cytometry (MC).
HostingRepositoryPRIDE
AnnounceDate2021-03-04
AnnouncementXMLSubmission_2021-03-03_22:55:59.602.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterKirk Hansen
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentBruker Daltonics BioTOF series
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-11-30 03:59:04ID requested
12021-03-03 22:55:59announced
Publication List
Dataset with its publication pending
Keyword List
ProteomeXchange project tag: Covid-19
submitter keyword: plasma, COVID-19, multi-omics
Contact List
Kirk Hansen
contact affiliationDepartment of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, USA
contact emailkirk.hansen@cuanschutz.edu
lab head
Kirk Hansen
contact affiliationUniversity of Colorado
contact emailkirk.hansen@ucdenver.edu
dataset submitter
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PRIDE project URI
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