PXD021076

PXD021076 is an original dataset announced via ProteomeXchange.

Title	Proteomics profiling of pediatric choroid plexus tumors
Description	Aggresome is a para nuclear inclusion body that functions as a storage compartment for misfolded proteins. Our previous work revealed the presence of aggresomes in pediatric choroid plexus tumors (CPT). CPTs are rare neoplasms comprised of three pathological subgroups; choroid plexus carcinoma (CPC), a grade III tumor, atypical choroid plexus papilloma (ACPP), a grade II tumor, and choroid plexus papilloma (CPP), a grade I tumor. In the current study, we aimed to investigate the prognostic value of aggresomes-positivity and its correlation to the pathological and molecular subtypes. The proteomics profiling of 21 CPT pediatric samples was investigated using ABSciex Triple TOF 5600+ mass spectrometer.
HostingRepository	PRIDE
AnnounceDate	2021-02-11
AnnouncementXML	Submission_2021-02-11_01:05:49.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD021076
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Nouran Al-Shehaby
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue; deamidated residue
Instrument	TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2020-08-24 02:38:47	ID requested
⏵ 1	2021-02-11 01:05:49	announced

Dataset with its publication pending

ProteomeXchange project tag: Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project

submitter keyword: Human, Pediatric, Cancer, Tumor, Choroid Plexus, Tissue, Pappiloma, Atypical, Carcinoma

Shahenda Mahmoud El-Naggar
contact affiliation	Tumor Biology Research Program, Basic Research Unit, Research Department, Children's Cancer Hospital Egypt 57357
contact email	shahenda.elnaggar@57357.org
lab head
Nouran Al-Shehaby
contact affiliation	Children's Cancer Hospital Egypt 57357
contact email	nouran.alshehaby@57357.org
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/02/PXD021076

PRIDE project URI

• PRIDE
  1. PXD021076
     1. Label: PRIDE project
     2. Name: Proteomics profiling of pediatric choroid plexus tumors