PXD020116

PXD020116 is an original dataset announced via ProteomeXchange.

Title	Quantitative Proteome of Infant Stenotic Ureters Reveals Extracellular Matrix Organization and Oxidative Stress Dysregulation Underlying Ureteropelvic Junction Obstruction
Description	Ureteropelvic junction obstruction (UPJO) is the most frequent cause of congenital hydronephrosis in child. To better investigate the molecular mechanisms of this pathological process, we performed data independent acquisition-based proteomics to compare the stenotic ureter proteome of UPJO in infants with their own normal pre-stenotic segments.
HostingRepository	iProX
AnnounceDate	2020-08-17
AnnouncementXML	Submission_2020-11-30_18:53:31.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yueyan Li
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	oxidation
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2020-06-29 21:54:24	ID requested
1	2020-06-29 21:58:53	announced
2	2020-08-17 20:19:20	announced	2020-08-18: Update information
⏵ 3	2020-11-30 18:53:32	announced	2020-08-18: Update information 2020-12-01: Update publication information

Li Y, Chen Z, Zhang J, Zhang Q, He L, Xu M, Xu G, Geng H, Fang X, Quantitative Proteome of Infant Stenotic Ureters Reveals Extracellular Matrix Organization and Oxidative Stress Dysregulation Underlying Ureteropelvic Junction Obstruction. Proteomics Clin Appl, 14(6):e2000030(2020) [pubmed]

submitter keyword: proteomics, ureteropelvic junction obstruction, congenital hydronephrosis, extracellular matrix, oxidative stress

Hongquan Geng
contact affiliation	Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine
contact email	genghongquan@xinhuamed.com.cn
lab head
Yueyan Li
contact affiliation	Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine
contact email	442152307@qq.com
dataset submitter

iProX dataset URI