<<< Full experiment listing

PXD019810

PXD019810 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleHDX-MS of VDR-RXR in complex with ZK168281
DescriptionCharacterization of the interaction between the full nuclear receptor VDR-RXR heterodimer and VDR antagonist ZK168281
HostingRepositoryPRIDE
AnnounceDate2020-12-16
AnnouncementXMLSubmission_2020-12-15_22:43:21.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAnna Belorusova
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentSynapt MS
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-06-16 08:30:44ID requested
12020-12-15 22:43:22announced
Publication List
Rovito D, Belorusova AY, Chalhoub S, Rerra AI, Guiot E, Molin A, Linglart A, Rochel N, Laverny G, Metzger D, Cytosolic sequestration of the vitamin D receptor as a therapeutic option for vitamin D-induced hypercalcemia. Nat Commun, 11(1):6249(2020) [pubmed]
Keyword List
submitter keyword: HDX-MS, nuclear receptors, antagonist
Contact List
Tomas Leek
contact affiliationMedicinal Chemistry, Early Respiratory and Immunology, Biopharmaceuticals R&D, AstraZeneca
contact emailTomas.Leek@astrazeneca.com
lab head
Anna Belorusova
contact affiliationMedicinal Chemistry, Early Respiratory and Inflammation, BioPharmaceuticals R&D, AstraZeneca
contact emailanna.y.belorusova@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
PRIDE project URI
Repository Record List
[ + ]