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PXD019645-2

PXD019645 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleData, reagents, assays and merits of proteomics for SARS-CoV-2 research and testing
DescriptionAs the SARS-CoV-2 pandemic continues to spread, thousands of scientists around the globe have changed research direction to understand better how the virus works and to find out how it may be tackled. To facilitate proteomic research on SARS-CoV-2, we presents deep-scale proteomes of common cell line models (Calu-3, Caco-2, ACE2 transfected A549 and Vero E6) and monitors changes of the proteome upon viral infection in Vero E6 cells. We provide high quality proteome expression data that can be used to refine the annotation of protein coding regions of the Vero E6 cell line genome. Further, we generated spectral libraries that can be used DIA cell line experiments or PRM assays of SARS-CoV-2 proteins.
HostingRepositoryPRIDE
AnnounceDate2020-06-30
AnnouncementXMLSubmission_2020-06-30_04:05:45.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterChien-Yun Lee
SpeciesList scientific name: Cercopithecus aethiops (Green monkey) (Grivet); NCBI TaxID: 9534; scientific name: Homo sapiens (Human); NCBI TaxID: 9606; scientific name: Chlorocebus sabaeus; NCBI TaxID: 60711;
ModificationListmonohydroxylated residue; N-acetylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-06-08 04:54:13ID requested
12020-06-28 23:18:01announced
22020-06-30 04:05:46announced2020-06-30: Updated publication reference for PubMed record(s): 32591346.
2020-06-30: Updated publication reference for DOI(s): 10.1074/mcp.RA120.002164.
Publication List
10.1074/mcp.RA120.002164;
Zecha J, Lee CY, Bayer FP, Meng C, Grass V, Zerweck J, Schnatbaum K, Michler T, Pichlmair A, Ludwig C, Kuster B, Data, Reagents, Assays and Merits of Proteomics for SARS-CoV-2 Research and Testing. Mol Cell Proteomics, 19(9):1503-1522(2020) [pubmed]
Keyword List
ProteomeXchange project tag: Sars-cov-2, Covid-19
submitter keyword: SARS-CoV-2, stable isotope labeling, parallel reaction monitoring, Vero E6, ACE2, infectome, COVID-19, clinical proteomics
Contact List
Bernhard Kuster
contact affiliationChair of Proteomics and Bioanalytics, Technical University of Munich, Germany
contact emailkuster@tum.de
lab head
Chien-Yun Lee
contact affiliationChair of Proteomics and Bioanalytics, Technical University of Munich (TUM)
contact emailchienyun.lee@tum.de
dataset submitter
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Dataset FTP location
PRIDE project URI
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