PXD019645 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Data, reagents, assays and merits of proteomics for SARS-CoV-2 research and testing |
Description | As the SARS-CoV-2 pandemic continues to spread, thousands of scientists around the globe have changed research direction to understand better how the virus works and to find out how it may be tackled. To facilitate proteomic research on SARS-CoV-2, we presents deep-scale proteomes of common cell line models (Calu-3, Caco-2, ACE2 transfected A549 and Vero E6) and monitors changes of the proteome upon viral infection in Vero E6 cells. We provide high quality proteome expression data that can be used to refine the annotation of protein coding regions of the Vero E6 cell line genome. Further, we generated spectral libraries that can be used DIA cell line experiments or PRM assays of SARS-CoV-2 proteins. |
HostingRepository | PRIDE |
AnnounceDate | 2020-06-30 |
AnnouncementXML | Submission_2020-06-30_04:05:45.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Chien-Yun Lee |
SpeciesList | scientific name: Cercopithecus aethiops (Green monkey) (Grivet); NCBI TaxID: 9534; scientific name: Homo sapiens (Human); NCBI TaxID: 9606; scientific name: Chlorocebus sabaeus; NCBI TaxID: 60711; |
ModificationList | monohydroxylated residue; N-acetylated residue; iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-06-08 04:54:13 | ID requested | |
1 | 2020-06-28 23:18:01 | announced | |
⏵ 2 | 2020-06-30 04:05:46 | announced | 2020-06-30: Updated publication reference for PubMed record(s): 32591346.
2020-06-30: Updated publication reference for DOI(s): 10.1074/mcp.RA120.002164. |
Publication List
10.1074/mcp.RA120.002164; |
Zecha J, Lee CY, Bayer FP, Meng C, Grass V, Zerweck J, Schnatbaum K, Michler T, Pichlmair A, Ludwig C, Kuster B, Data, Reagents, Assays and Merits of Proteomics for SARS-CoV-2 Research and Testing. Mol Cell Proteomics, 19(9):1503-1522(2020) [pubmed] |
Keyword List
ProteomeXchange project tag: Sars-cov-2, Covid-19 |
submitter keyword: SARS-CoV-2, stable isotope labeling, parallel reaction monitoring, Vero E6, ACE2, infectome, COVID-19, clinical proteomics |
Contact List
Bernhard Kuster |
contact affiliation | Chair of Proteomics and Bioanalytics, Technical University of Munich, Germany |
contact email | kuster@tum.de |
lab head | |
Chien-Yun Lee |
contact affiliation | Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM) |
contact email | chienyun.lee@tum.de |
dataset submitter | |
Full Dataset Link List
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD019645
- Label: PRIDE project
- Name: Data, reagents, assays and merits of proteomics for SARS-CoV-2 research and testing