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PXD019255-1

PXD019255 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleUncovering tumor-stroma inter-relationships using quantitative MALDI-Mass spectrometry imaging
DescriptionTo facilitate analysis of protein expression changes in in situ tumors and stroma, we took advantage of a mouse model that permits conditional activation of the Ser-Thr kinase ROCK within mammary tumor cells. In this study, we undertook MALDI-MSI analysis of tissue samples derived from our conditional ROCK mammary tumor model, to quantify in an unbiased manner, the proteomic changes occurring during the progression of mammary cancers in their specific spatial contexts.
HostingRepositoryPRIDE
AnnounceDate2020-09-07
AnnouncementXMLSubmission_2020-09-07_00:10:48.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterParul Mittal
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumentLTQ; ultraflex
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-05-18 02:46:55ID requested
12020-09-07 00:10:49announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: MALDI imaging, Breast cancer, stroma, extra-cellular matrix, trafficking
Contact List
Manuela Klingler-Hoffmann
contact affiliationResearch Fellow Future Industries Institute | University of South Australia ipc MLK-40 | p GPO Box 2471 Adelaide SA 5001
contact emailManuela.Klingler-Hoffmann@unisa.edu.au
lab head
Parul Mittal
contact affiliationResearch associate
contact emailpearl106@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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