PXD019255

PXD019255 is an original dataset announced via ProteomeXchange.

Title	Uncovering tumor-stroma inter-relationships using quantitative MALDI-Mass spectrometry imaging
Description	To facilitate analysis of protein expression changes in in situ tumors and stroma, we took advantage of a mouse model that permits conditional activation of the Ser-Thr kinase ROCK within mammary tumor cells. In this study, we undertook MALDI-MSI analysis of tissue samples derived from our conditional ROCK mammary tumor model, to quantify in an unbiased manner, the proteomic changes occurring during the progression of mammary cancers in their specific spatial contexts.
HostingRepository	PRIDE
AnnounceDate	2020-09-07
AnnouncementXML	Submission_2020-09-07_00:10:48.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Parul Mittal
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ; ultraflex

Revision	Datetime	Status	ChangeLog Entry
0	2020-05-18 02:46:55	ID requested
⏵ 1	2020-09-07 00:10:49	announced

Dataset with its publication pending

submitter keyword: MALDI imaging, Breast cancer, stroma, extra-cellular matrix, trafficking

Manuela Klingler-Hoffmann
contact affiliation	Research Fellow Future Industries Institute | University of South Australia ipc MLK-40 | p GPO Box 2471 Adelaide SA 5001
contact email	Manuela.Klingler-Hoffmann@unisa.edu.au
lab head
Parul Mittal
contact affiliation	Research associate
contact email	pearl106@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/09/PXD019255

PRIDE project URI

• PRIDE
  1. PXD019255
     1. Label: PRIDE project
     2. Name: Uncovering tumor-stroma inter-relationships using quantitative MALDI-Mass spectrometry imaging