PXD018874 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | High-throughput proteomics platform for clinical applications |
Description | Clinical proteomics holds the promise to accelerate the discovery of disease biomarkers, as well as to predict disease trajectories. Here we present a new platform for high-throughput plasma and serum proteomics, which combines an automated sample preparation workflow, robust high-flow liquid chromatography, and an optimized SWATH-MS acquisition scheme as well as data processing workflow. The process requires as little as 5uL serum or plasma and makes use of fast 5-minute chromatographic gradients. The dataset shows the robustness and precision of the workflow and consists of commercial plasma and serum samples that were distributed in 4 different 96 well plates and injected within a sample series of 417 serum injections. Further, the dataset includes of injections of a single sample (pooled from 32 prepared commercial serum samples) every 10 injections. |
HostingRepository | PRIDE |
AnnounceDate | 2020-06-09 |
AnnouncementXML | Submission_2020-06-09_06:23:02.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Christoph Messner |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | iodoacetamide derivatized residue |
Instrument | TripleTOF 6600 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-04-28 16:51:02 | ID requested | |
⏵ 1 | 2020-06-09 06:23:03 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: High-throughput proteomics, plasma, serum, clinical proteomics |
Contact List
Markus Ralser |
contact affiliation | Charite- Universitaetsmedizin Berlin, 10117 Berlin, Germany |
contact email | markus.ralser@charite.de |
lab head | |
Christoph Messner |
contact affiliation | Francis Crick Institute |
contact email | christoph.messner@crick.ac.uk |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD018874 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD018874
- Label: PRIDE project
- Name: High-throughput proteomics platform for clinical applications