PXD018730 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Synergistic effects between rutin and ascorbic acid in the protection of the proteome of 3D-cultured human skin fibroblasts from UVA radiation |
Description | This study demonstrates the cooperation of rutin and ascorbic acid in cytoprotective action against UVA induced changes in the context of proteins involved in gene expression, catalytic processes, antioxidant pathways, as well as signalling molecules including transmembrane channels. The main advantages of the work is application in research a three-dimensional (3D) cell culturing system providing the most epidermal-like conditions. |
HostingRepository | PRIDE |
AnnounceDate | 2020-11-20 |
AnnouncementXML | Submission_2020-11-20_08:00:56.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Agnieszka Gęgotek |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-04-22 05:17:58 | ID requested | |
⏵ 1 | 2020-11-20 08:00:57 | announced | |
Publication List
G, ę, gotek A, Domingues P, Skrzydlewska E, Natural Exogenous Antioxidant Defense against Changes in Human Skin Fibroblast Proteome Disturbed by UVA Radiation. Oxid Med Cell Longev, 2020():3216415(2020) [pubmed] |
Keyword List
submitter keyword: skin fibroblasts |
UVA radiation |
rutin |
ascorbic acid |
proteomics |
3D cell culture |
Contact List
Agnieszka Gegotek |
contact affiliation | Department of Analytical Chemistry, Medical University of Bialystok; Mickiewicza 2D, 15-222 Bialystok, Poland; |
contact email | agnieszka.gegotek@umb.edu.pl |
lab head | |
Agnieszka Gęgotek |
contact affiliation | Department of Analytical Chemistry, Medical University of Bialystok, Mickiewicza 2D, 15-222 Bialystok, Poland |
contact email | agnieszka.gegotek@umb.edu.pl |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/11/PXD018730 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD018730
- Label: PRIDE project
- Name: Synergistic effects between rutin and ascorbic acid in the protection of the proteome of 3D-cultured human skin fibroblasts from UVA radiation