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PXD018730 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleSynergistic effects between rutin and ascorbic acid in the protection of the proteome of 3D-cultured human skin fibroblasts from UVA radiation
DescriptionThis study demonstrates the cooperation of rutin and ascorbic acid in cytoprotective action against UVA induced changes in the context of proteins involved in gene expression, catalytic processes, antioxidant pathways, as well as signalling molecules including transmembrane channels. The main advantages of the work is application in research a three-dimensional (3D) cell culturing system providing the most epidermal-like conditions.
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAgnieszka Gęgotek
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-04-22 05:17:58ID requested
12020-11-20 08:00:57announced
Publication List
Gęgotek A, Domingues P, Skrzydlewska E, Natural Exogenous Antioxidant Defense against Changes in Human Skin Fibroblast Proteome Disturbed by UVA Radiation. Oxid Med Cell Longev, 2020():3216415(2020) [pubmed]
Keyword List
submitter keyword: skin fibroblasts
UVA radiation
ascorbic acid
3D cell culture
Contact List
Agnieszka Gegotek
contact affiliationDepartment of Analytical Chemistry, Medical University of Bialystok; Mickiewicza 2D, 15-222 Bialystok, Poland;
contact emailagnieszka.gegotek@umb.edu.pl
lab head
Agnieszka Gęgotek
contact affiliationDepartment of Analytical Chemistry, Medical University of Bialystok, Mickiewicza 2D, 15-222 Bialystok, Poland
contact emailagnieszka.gegotek@umb.edu.pl
dataset submitter
Full Dataset Link List
Dataset FTP location
PRIDE project URI
Repository Record List
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