PXD018608-1

PXD018608 is an original dataset announced via ProteomeXchange.

Title	Crosslinking/mass spectrometry (CLMS) analysis of Cohesin complex
Description	The ring-shaped cohesin complex is thought to fulfil its roles in sister chromatid cohesion, genome stability and gene regulation by topologically encircling DNAs. The ring is formed by two Structural Maintenance of Chromosome (SMC) subunits, whose ATPase heads are linked by a kleisin subunit. Additional components, including the Mis4Scc2/NIPL cohesin loader, engage the kleisin. We applied crosslinking mass spectrometry to characterize cohesion complex in two conditions: initial binding and gripping state.
HostingRepository	PRIDE
AnnounceDate	2020-08-04
AnnouncementXML	Submission_2020-08-04_00:11:59.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Zhuo Chen
SpeciesList	scientific name: Schizosaccharomyces pombe 972h-; NCBI TaxID: 284812;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2020-04-16 23:00:04	ID requested
⏵ 1	2020-08-04 00:12:00	announced

Dataset with its publication pending

submitter keyword: crosslinking/mass spectrometry, cohesin complex

Juri Rappsilber
contact affiliation	Technische Universität Berlin The University of Edinburgh
contact email	juri.rappsilber@tu-berlin.de
lab head
Zhuo Chen
contact affiliation	Technischen Universität Berlin
contact email	zhuo.chen@tu-berlin.de
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD018608
     1. Label: PRIDE project
     2. Name: Crosslinking/mass spectrometry (CLMS) analysis of Cohesin complex