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PXD018608 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleCrosslinking/mass spectrometry (CLMS) analysis of Cohesin complex
DescriptionThe ring-shaped cohesin complex is thought to fulfil its roles in sister chromatid cohesion, genome stability and gene regulation by topologically encircling DNAs. The ring is formed by two Structural Maintenance of Chromosome (SMC) subunits, whose ATPase heads are linked by a kleisin subunit. Additional components, including the Mis4Scc2/NIPL cohesin loader, engage the kleisin. We applied crosslinking mass spectrometry to characterize cohesion complex in two conditions: initial binding and gripping state.
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterZhuo Chen
SpeciesList scientific name: Schizosaccharomyces pombe 972h-; NCBI TaxID: 284812;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-04-16 23:00:04ID requested
12020-08-04 00:12:00announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: crosslinking/mass spectrometry, cohesin complex
Contact List
Juri Rappsilber
contact affiliationTechnische Universit├Ąt Berlin The University of Edinburgh
contact emailjuri.rappsilber@tu-berlin.de
lab head
Zhuo Chen
contact affiliationTechnischen Universit├Ąt Berlin
contact emailzhuo.chen@tu-berlin.de
dataset submitter
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