PXD017154 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | T-cell alloreactivity to HLA-DP is regulated by peptide repertoire divergence and HLA-DM mediated editing |
Description | Analysis of the peptide repertoires eluted from different HLA-DP molecules expressed in HeLa cells co-expressing Invariant chain either with or without HLA-DM as components of the HLA class II processing machinery. Divergence of the immunopeptidomes and the impact of HLA-DM were investigated in relation to the capacity of HLA-DP molecules to elicit alloreactive T-cell responses. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_08:50:50.881.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD017154 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Pietro Crivello |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | Oxidation; monohydroxylated residue |
Instrument | Orbitrap Fusion Lumos; LTQ Orbitrap Elite |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-01-16 07:41:59 | ID requested | |
1 | 2022-11-21 08:47:09 | announced | |
⏵ 2 | 2023-11-14 08:50:51 | announced | 2023-11-14: Updated project metadata. |
Publication List
Dataset with its publication pending |
Keyword List
curator keyword: Biological |
submitter keyword: HLA class II, HLA-DM, immunopeptidome, HLA-DP, T-cell alloreactivity |
Contact List
Katharina Fleischhauer |
contact affiliation | Institute for Experimental Cellular Therapy, University Hospital Essen, Essen, Germany |
contact email | fleischhauer.katharina@uk-essen.de |
lab head | |
Pietro Crivello |
contact affiliation | Institute for Experimental Cellular Therapy |
contact email | pietro.crivello@uk-essen.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/11/PXD017154 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD017154
- Label: PRIDE project
- Name: T-cell alloreactivity to HLA-DP is regulated by peptide repertoire divergence and HLA-DM mediated editing