PXD016183-2
PXD016183 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Phosphoproteomics reveals key regulatory kinases and modulated pathways involved in tumorigenesis of ovarian cancer |
Description | The present study comprehensively revealed the molecular characteristics in relation to OC and identified significantly distinct phosphorylated sites and phosphorylated proteins underlying the syndrome. The results here dissected regulatory elements (especially kinases) and pathways involved in cancer-related pathways including fructose & mannose metabolism, MAPK, ErbB, and ErbB signaling pathway. These findings may not only provide potential biomarkers and novel therapeutic targets for OC, but also bolstered our knowledge on the physiopathology of this syndrome. |
HostingRepository | iProX |
AnnounceDate | 2019-12-31 |
AnnouncementXML | Submission_2020-12-16_19:36:54.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Jun Rao |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | phosphorylated residue |
Instrument | Orbitrap Fusion |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2019-11-06 19:38:30 | ID requested | |
1 | 2020-01-01 19:15:09 | announced | |
⏵ 2 | 2020-12-16 19:36:55 | announced | 2020-12-02: Update publication information |
Publication List
Hu Y, Sun L, Zhang Y, Lang J, Rao J, Phosphoproteomics Reveals Key Regulatory Kinases and Modulated Pathways Associated with Ovarian Cancer Tumors. Onco Targets Ther, 13():3595-3605(2020) [pubmed] |
Keyword List
submitter keyword: ovarian cancer, phosphoproteomics, Ti4+-IMAC, kinases, biomarker |
Contact List
Jinghe Lang | |
---|---|
contact affiliation | Chinese Academy of Medical Sciences and Peking Union Medical College |
contact email | langjh2019@126.com |
lab head | |
Jun Rao | |
contact affiliation | Jiangxi Cancer Hospital |
contact email | raojun1986@126.com |
dataset submitter |
Full Dataset Link List
iProX dataset URI |