PXD016183

PXD016183 is an original dataset announced via ProteomeXchange.

Title	Phosphoproteomics reveals key regulatory kinases and modulated pathways involved in tumorigenesis of ovarian cancer
Description	The present study comprehensively revealed the molecular characteristics in relation to OC and identified significantly distinct phosphorylated sites and phosphorylated proteins underlying the syndrome. The results here dissected regulatory elements (especially kinases) and pathways involved in cancer-related pathways including fructose & mannose metabolism, MAPK, ErbB, and ErbB signaling pathway. These findings may not only provide potential biomarkers and novel therapeutic targets for OC, but also bolstered our knowledge on the physiopathology of this syndrome.
HostingRepository	iProX
AnnounceDate	2019-12-31
AnnouncementXML	Submission_2020-12-16_19:36:54.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jun Rao
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	phosphorylated residue
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2019-11-06 19:38:30	ID requested
1	2020-01-01 19:15:09	announced
⏵ 2	2020-12-16 19:36:55	announced	2020-12-02: Update publication information

Hu Y, Sun L, Zhang Y, Lang J, Rao J, Phosphoproteomics Reveals Key Regulatory Kinases and Modulated Pathways Associated with Ovarian Cancer Tumors. Onco Targets Ther, 13():3595-3605(2020) [pubmed]

submitter keyword: ovarian cancer, phosphoproteomics, Ti4+-IMAC, kinases, biomarker

Jinghe Lang
contact affiliation	Chinese Academy of Medical Sciences and Peking Union Medical College
contact email	langjh2019@126.com
lab head
Jun Rao
contact affiliation	Jiangxi Cancer Hospital
contact email	raojun1986@126.com
dataset submitter

iProX dataset URI