PXD015936 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Quantitative phosphoproteomics analysis uncovers the regulatory networks of ZNF322A in lung cancer cells |
Description | Cys2His2 (C2H2)-type zinc finger (ZNF) is one of the most common DNA-binding motif and plays a major role as transcription factors, which encoded by 2% of human genes. C2H2 type ZNFs are reported as proteins of great versatility, such as regulation of differentiation, development, metabolism, cell survival, apoptosis, and autophagy. To uncover ZNF322A-mediated functional network, we applied phosphopeptide enrichment and isobaric labeling strategies with MS-based proteomics, and identified 2754 phosphorylation sites on 976 phosphoproteins. |
HostingRepository | PRIDE |
AnnounceDate | 2021-09-08 |
AnnouncementXML | Submission_2021-09-08_11:41:09.783.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Chantal Hoi Yin Cheung |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | phosphorylated residue |
Instrument | LTQ Orbitrap Elite |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2019-10-21 04:08:09 | ID requested | |
⏵ 1 | 2021-09-08 11:41:10 | announced | |
Publication List
Cheung CHY, Hsu CL, Lin TY, Chen WT, Wang YC, Huang HC, Juan HF, ZNF322A-mediated protein phosphorylation induces autophagosome formation through modulation of IRS1-AKT glucose uptake and HSP-elicited UPR in lung cancer. J Biomed Sci, 27(1):75(2020) [pubmed] |
Keyword List
submitter keyword: Human lung cancer, ZNF322A, phosphoproteomics |
Contact List
Hsueh-Fen Juan, Ph.D. |
contact affiliation | Department of Life Science, National Taiwan University |
contact email | yukijuan@ntu.edu.tw |
lab head | |
Chantal Hoi Yin Cheung |
contact affiliation | national taiwan university |
contact email | hycchantal@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD015936
- Label: PRIDE project
- Name: Quantitative phosphoproteomics analysis uncovers the regulatory networks of ZNF322A in lung cancer cells