PXD014929

PXD014929 is an original dataset announced via ProteomeXchange.

Title	Mass spectrometry analysis following chromatin fractionation in growing and senescent cells
Description	This project contains the raw and result files for a mass spectrometry analysis comparing the abundance of proteins following chromatin fractionation in growing cells and in senescent cells for the WI-38hTERT/GFP-RAF1-ER cell line. Two replicas were analysed for each cell condition. The data are used to support a study on using polymer modelling to investigate the roles of heterochromatin and lamina interactions on chromosome reorganisation in senescence.
HostingRepository	PRIDE
AnnounceDate	2019-09-25
AnnouncementXML	Submission_2019-10-25_05:23:42.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD014929
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Michael Chiang
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	L-cysteine residue; residues isobaric at 113.084064 Da; residues isobaric at 128.058578 Da; Deamidated; TMT6plex; L-tyrosine residue; Oxidation; Carbamidomethyl; residues isobaric at 71.037114 Da
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2019-08-06 05:34:25	ID requested
1	2019-09-25 10:47:53	announced
⏵ 2	2019-10-25 05:23:43	announced	2019-10-25: Updated publication reference for PubMed record(s): 31533042.

Chiang M, Michieletto D, Brackley CA, Rattanavirotkul N, Mohammed H, Marenduzzo D, Chandra T, Polymer Modeling Predicts Chromosome Reorganization in Senescence. Cell Rep, 28(12):3212-3223.e6(2019) [pubmed]

submitter keyword: Human, lung fibroblast, LC-MSMS

Hisham Mohammed
contact affiliation	Cancer Early Detection Advanced Research Center, Knight Cancer Institute, Department of Molecular & Medical Genetics, Oregon Health & Science University, Portland, OR 97239, U.S.A.
contact email	mohammeh@ohsu.edu
lab head
Michael Chiang
contact affiliation	University of Edinburgh
contact email	c.h.m.chiang@sms.ed.ac.uk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/09/PXD014929

PRIDE project URI

• PRIDE
  1. PXD014929
     1. Label: PRIDE project
     2. Name: Mass spectrometry analysis following chromatin fractionation in growing and senescent cells