PXD014685-2

PXD014685 is an original dataset announced via ProteomeXchange.

Title	iTRAQ-based phospho-proteomics identifies a critical role of ATF2 in pseudorabies virus replication
Description	Pseudorabies virus (PRV), the etiological agent of Aujeszky’s disease, is a swine pathogen of the alphaherpesvirinae subfamily resulting in devastating neurological and respiratory disorders in piglets, or abortion in pregnant sows.Here, we performed isobaric tags for relative and absolute quantitation (iTRAQ) quantitative phosphoproteomics on PRV-infected PK-15 cells, which identified 5723 phospho-peptides, corresponding to 2180 proteins, including 810 proteins showing significant changes in phosphorylation level during early PRV infection.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_07:32:38.259.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Zheng-Fei Liu
SpeciesList	scientific name: Bos taurus (Bovine); NCBI TaxID: 9913;
ModificationList	phosphorylated residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2019-07-22 05:46:16	ID requested
1	2022-10-13 05:05:55	announced
⏵ 2	2023-11-14 07:32:40	announced	2023-11-14: Updated project metadata.

Jiang FF, Wang RQ, Guo CY, Zheng K, Liu HL, Su L, Xie SS, Chen HC, Liu ZF, Phospho-proteomics identifies a critical role of ATF2 in pseudorabies virus replication. Virol Sin, 37(4):591-600(2022) [pubmed]

submitter keyword: pseudorabies virus, phosphorylation, iTRAQ, ATF2

Zheng-Fei Liu
contact affiliation	State Key Laboratory of Agricultural Microbiology and Key laboratory of Preventive Veterinary Medicine in Hubei Province, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, P. R. China
contact email	lzf6789@mail.hzau.edu.cn
lab head
Zheng-Fei Liu
contact affiliation	Huazhong Agricultural
contact email	lzf6789@mail.hzau.edu.cn
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/10/PXD014685

PRIDE project URI

• PRIDE
  1. PXD014685
     1. Label: PRIDE project
     2. Name: iTRAQ-based phospho-proteomics identifies a critical role of ATF2 in pseudorabies virus replication