PXD013594-1

PXD013594 is an original dataset announced via ProteomeXchange.

Title	Investigating the dynamics of the SecA–SecYEG complex dynamic by HDX-MS
Description	We employ hydrogen-deuterium exchange mass spectrometry (HDX-MS) to investigate the conformational dynamics required to facilitate based Brownian ratchet mechanism for protein secretion (by the SecA-SecYEG complex).
HostingRepository	PRIDE
AnnounceDate	2019-07-16
AnnouncementXML	Submission_2019-07-16_04:33:56.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Zainab Ahdash
SpeciesList	scientific name: Escherichia coli; NCBI TaxID: 562;
ModificationList	No PTMs are included in the dataset
Instrument	Synapt MS

Revision	Datetime	Status	ChangeLog Entry
0	2019-04-23 02:45:46	ID requested
⏵ 1	2019-07-16 04:33:57	announced

Ahdash Z, Pyle E, Allen WJ, Corey RA, Collinson I, Politis A, HDX-MS reveals nucleotide-dependent, anti-correlated opening and closure of SecA and SecY channels of the bacterial translocon. Elife, 8():(2019) [pubmed]

submitter keyword: SecA–SecYEG, HDX-MS

Argyris Politis
contact affiliation	Lecturer in Chemical Systems Biology Department of Chemistry King's College London
contact email	argyris.politis@kcl.ac.uk
lab head
Zainab Ahdash
contact affiliation	King's College London
contact email	zainab.ahdash@kcl.ac.uk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/07/PXD013594

PRIDE project URI

• PRIDE
  1. PXD013594
     1. Label: PRIDE project
     2. Name: Investigating the dynamics of the SecA–SecYEG complex dynamic by HDX-MS