PXD013388-1

PXD013388 is an original dataset announced via ProteomeXchange.

Title	Programmable polyketide biosynthesis platform for production of aromatic compounds in yeast
Description	To accelerate the shift to bio-based production and overcome complicated functional implementation of natural and artificial biosynthetic pathways to industry relevant organisms, development of new, versatile, bio-based production platforms are required. Here we present a novel yeast platform for biosynthesis of bacterial aromatic polyketides. The platform is based on a synthetic polyketide synthase system enabling a first demonstration of aromatic polyketide biosynthesis in a eukaryotic host.
HostingRepository	PanoramaPublic
AnnounceDate	2020-02-11
AnnouncementXML	Submission_2020-02-11_09:20:25.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Chris Petzold
SpeciesList	scientific name: Saccharomyces cerevisiae; NCBI TaxID: 4932;
ModificationList	Carbamidomethyl
Instrument	6460 Triple Quadrupole LC/MS

Revision	Datetime	Status	ChangeLog Entry
0	2019-04-06 13:11:02	ID requested
⏵ 1	2020-02-11 09:20:26	announced

Jako, č, i, ū, nas T, Klitgaard AK, Kontou EE, Nielsen JB, Thomsen E, Romero-Suarez D, Blin K, Petzold CJ, Gin JW, Tong Y, Gotfredsen CH, Charusanti P, Frandsen RJN, Weber T, Lee SY, Jensen MK, Keasling JD, Programmable polyketide biosynthesis platform for production of aromatic compounds in yeast. Synth Syst Biotechnol, 5(1):11-18(2020) [pubmed]

submitter keyword: Metabolic engineering, polyketides, S. cerevisiae, Targeted proteomics

Chris Petzold
contact affiliation	Lawrence Berkeley National Laboratory
contact email	cjpetzold@lbl.gov
lab head
Chris Petzold
contact affiliation	Lawrence Berkeley National Laboratory
contact email	cjpetzold@lbl.gov
dataset submitter

Panorama Public dataset URI