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PXD013388

PXD013388 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProgrammable polyketide biosynthesis platform for production of aromatic compounds in yeast
DescriptionTo accelerate the shift to bio-based production and overcome complicated functional implementation of natural and artificial biosynthetic pathways to industry relevant organisms, development of new, versatile, bio-based production platforms are required. Here we present a novel yeast platform for biosynthesis of bacterial aromatic polyketides. The platform is based on a synthetic polyketide synthase system enabling a first demonstration of aromatic polyketide biosynthesis in a eukaryotic host.
HostingRepositoryPanoramaPublic
AnnounceDate2020-02-11
AnnouncementXMLSubmission_2020-02-11_09:20:25.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterChris Petzold
SpeciesList scientific name: Saccharomyces cerevisiae; NCBI TaxID: 4932;
ModificationListCarbamidomethyl
Instrument6460 Triple Quadrupole LC/MS
Dataset History
RevisionDatetimeStatusChangeLog Entry
02019-04-06 13:11:02ID requested
12020-02-11 09:20:26announced
Publication List
Jakočiūnas T, Klitgaard AK, Kontou EE, Nielsen JB, Thomsen E, Romero-Suarez D, Blin K, Petzold CJ, Gin JW, Tong Y, Gotfredsen CH, Charusanti P, Frandsen RJN, Weber T, Lee SY, Jensen MK, Keasling JD, Programmable polyketide biosynthesis platform for production of aromatic compounds in yeast. Synth Syst Biotechnol, 5(1):11-18(2020) [pubmed]
Keyword List
submitter keyword: Metabolic engineering, polyketides, S. cerevisiae, Targeted proteomics
Contact List
Chris Petzold
contact affiliationLawrence Berkeley National Laboratory
contact emailcjpetzold@lbl.gov
lab head
Chris Petzold
contact affiliationLawrence Berkeley National Laboratory
contact emailcjpetzold@lbl.gov
dataset submitter
Full Dataset Link List
Panorama Public dataset URI