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PXD012087

DataSet Summary

  • HostingRepository: PRIDE
  • AnnounceDate: 2019-07-11
  • AnnouncementXML: Submission_2019-07-11_01:13:18.xml
  • DigitalObjectIdentifier:
  • ReviewLevel: Peer-reviewed dataset
  • DatasetOrigin: Original data
  • RepositorySupport: Unsupported dataset by repository
  • PrimarySubmitter: Jason Wong
  • Title: Kinome profiling of Non-Hodgkin Lymphoma identifies Tyro3 as a therapeutic target in PEL
  • Description: Non-Hodgkin lymphomas (NHL) make up the majority of lymphoma diagnoses and represent a very diverse set of malignancies. We sought to identify kinases uniquely upregulated in different NHL subtypes. Using Multiplexed Inhibitor Bead-mass spectrometry (MIB/MS), we found Tyro3 was uniquely upregulated and important for cell survival in primary effusion lymphoma (PEL), which is a viral lymphoma infected with Kaposi‚Äôs sarcoma-associated herpesvirus (KSHV).
  • SpeciesList: scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
  • ModificationList: phosphorylated residue; acetylated residue; monohydroxylated residue; deamidated residue
  • Instrument: Q Exactive

Dataset History

VersionDatetimeStatusChangeLog Entry
02018-12-17 07:14:13ID requested
12019-07-11 01:13:19announced

Publication List

  1. Dataset with its publication pending

Keyword List

  1. submitter keyword: Kinome profiling, Non-Hodgkin lymphoma, primary effusion lymphoma, Tyro3

Contact List

    Blossom Andrea Damania
    • contact affiliation: Department of Microbiology and Immunology and Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, 27599, USA.
    • contact email: damania@med.unc.edu
    • lab head:
    Jason Wong
    • contact affiliation: University of North Carolina at Chapel Hill
    • contact email: wongjp@email.unc.edu
    • dataset submitter:

Full Dataset Link List

  1. Dataset FTP location
  2. PRIDE project URI
Repository Record List
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