PXD011937

PXD011937 is an original dataset announced via ProteomeXchange.

Title	Proteomics characterization of Chromosomal Common Fragile Site (CFS) - associated proteins uncovers ATRX as a regulator of CFS stability
Description	Chromosomal Common Fragile Sites (CFSs) are conserved regions of our genome prone to break in conditions of replication stress (RS. Here, we have performed Chromatin Immunoprecipitation (ChIP) with FACND2 antibodies coupled to Mass Spectrometry to isolate CFSs from HeLa cells and identify the proteins enriched at these loci.
HostingRepository	PRIDE
AnnounceDate	2019-06-11
AnnouncementXML	Submission_2019-06-12_00:28:08.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Stephanie Munk
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2018-12-05 02:01:59	ID requested
1	2019-06-11 08:15:16	announced
⏵ 2	2019-06-12 00:28:09	announced	Updated publication reference for PubMed record(s): 31180492.

Pladevall-Morera D, Munk S, Ingham A, Garribba L, Albers E, Liu Y, Olsen JV, Lopez-Contreras AJ, Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability. Nucleic Acids Res, 47(15):8004-8018(2019) [pubmed]

curator keyword: Biological

submitter keyword: Common fragile sites, LC-MS/MS, HeLa, interactome, ATRX

Andres Joaquin Lopez-Contreras
contact affiliation	Department of Cellular and Molecular Medicine, Center for Chromosome Stability and Center for Healthy Aging, University of Copenhagen, Copenhagen 2200, Denmark
contact email	ajlopez@sund.ku.dk
lab head
Stephanie Munk
contact affiliation	Copenhagen University
contact email	wtv380@cpr.ku.dk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/06/PXD011937

PRIDE project URI

• PRIDE
  1. PXD011937
     1. Label: PRIDE project
     2. Name: Proteomics characterization of Chromosomal Common Fragile Site (CFS) - associated proteins uncovers ATRX as a regulator of CFS stability