PXD011647

PXD011647 is an original dataset announced via ProteomeXchange.

Title	LC-MS/MS of Human Plasma Peptides
Description	Discrepancies in blood sample collection and processing could have a significant impact on levels of peptides in the blood, thus sample quality control is critical for successful biomarker identification and validation. In this study, we analyzed the effects of several pre-analytical processing conditions, including different storage times and temperatures of blood or plasma samples and different centrifugation forces, on the levels of peptides in human plasma samples using ethylenediaminetetraacetic acid (EDTA) as an anticoagulant. Both time and temperature were identified as major factors for peptide variation.
HostingRepository	PRIDE
AnnounceDate	2022-02-15
AnnouncementXML	Submission_2022-02-15_09:10:18.241.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Li-Rong Yu
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2018-11-09 08:23:06	ID requested
⏵ 1	2022-02-15 09:10:19	announced

Cao Z, Kamlage B, Wagner-Golbs A, Maisha M, Sun J, Schnackenberg LK, Pence L, Schmitt TC, Daniels JR, Rogstad S, Beger RD, Yu LR, An Integrated Analysis of Metabolites, Peptides, and Inflammation Biomarkers for Assessment of Preanalytical Variability of Human Plasma. J Proteome Res, 18(6):2411-2421(2019) [pubmed]

submitter keyword: Human, plasma, peptides, LC-MS/MS

Li-Rong Yu
contact affiliation	Biomarkers and Alternative Models Branch Division of Systems Biology National Center for Toxicological Research U.S. Food and Drug Administration 3900 NCTR Rd., HFT-233 Jefferson, AR 72079 USA
contact email	lirong.yu@fda.hhs.gov
lab head
Li-Rong Yu
contact affiliation	National Center for Toxicological Research, FDA
contact email	lirong.yu@fda.hhs.gov
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/02/PXD011647

PRIDE project URI

• PRIDE
  1. PXD011647
     1. Label: PRIDE project
     2. Name: LC-MS/MS of Human Plasma Peptides